Figure 5

Figure 5: FABP7 protein expression is associated with survival in independent cohorts of GBM patients and enhances glioma cell motility in vitro.

(A) Kaplan-Meier analysis of nuclear FABP7 protein expression in an independent cohort of 44 GBM patients. FABP7 immunoreactivity (orange for score 0, blue for score of 1 or 2) correlates with survival in this group of patients (p<0.00005). (B) SF767MG cells were transfected as indicated and plated in the upper chamber of a transwell system (see Methods). Results represent average number of migrated cells in 3 separate transfections. Error bars represent standard error of the mean. *: p<0.001.