Figure 4:
Cell line-dependent gene expression patterns.
Data for cell line specific clusters are shown with the same color
scheme as in Figure 1. Clusters of genes whose expression was A)
repressed by stress in fibroblasts, B) induced by stress in HeLa cells
or C) induced by redox stress in fibroblasts were produced using the
2-step clustering method described in the methods. D) We extracted
and clustered the data for 1134 clones found to be cell cycle
regulated by (Whitfield et al., 2002). The genes shown are the core
of the resulting cluster and contain the most strongly cell
cycle-regulated genes. E) Data for all of the
genes encoding ribosomal proteins present on the arrays were extracted
and the genes were ordered by hierarchical clustering.
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