Gene expression programs in response to hypoxia; cell type specificity and prognostic significance in human cancers

Jen-Tsan Chi*, Zhen Wang*, Dimitry S.A. Nuyten, Edwin H. Rodriguez, Marci E. Schaner, Ali Salim, Yun Wang, Gunnar B. Kristensen, Åslaug Helland, Anne-Lise Børresen-Dale, Amato Giaccia, Michael T. Longaker, Trevor Hastie, George P. Yang, Marc J. van de Vijver, and Patrick O. Brown

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Data for individual microarrays will be publicly available for download through the Stanford Microarray Database upon publication. Our microarray data were also deposited in the GEO database and assigned the accession number GSE3537.


The processed microarray data for each of the figures can be downloaded below and viewed in TreeView. Data were selected, filtered, and normalized as described in the respective figure legends and in the Materials and Methods section.

Figure 1: Overview of the Genomic Responses to Hypoxia.

Figure 2: Cell Type-Specific Hypoxia Response.

Figure 3: Elevated HIF-1a in RPTECs and Its Role in RPTEC Hypoxia Response.

Figure 4: The Analysis of Hypoxia Response in Human Cancers.

 


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